Targeting the entry region of Hsp90's ATP binding pocket with a novel 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl amide. Jeong JH, Oh YJ, Lho Y, Park SY, Liu KH, Ha E, Seo YH. Eur J Med Chem. 2016, 124, 1069-1080.

Chalcone-templated Hsp90 inhibitors and their effects on gefitinib resistance in non-small cell lung cancer (NSCLC). Jeong JH, Oh YJ, Kwon TK, Seo YH. Arch Pharm Res. 2016, Oct 21. [Epub ahead of print]

Organelle-specific Hsp90 inhibitors. Seo YH. Arch Pharm Res. 2015, 9, 1582-90.

In Vitro Antifungal Activity and Mode of Action of 2',4'-Dihydroxychalcone against Aspergillus fumigatus. Seo YH, Kim SS, Shin KS. Mycobiology. 2015, 2, 150-6.

Dual Inhibitors Against Topoisomerases and Histone Deacetylases. Seo YH. J Cancer Prev. 2015, 2, 85-91.

Discovery of 2',4'-dimethoxychalcone as a Hsp90 inhibitor and its effect on iressa-resistant non-small cell lung cancer (NSCLC). Seo YH. Arch Pharm Res. 2015, 10, 1783-8.

Small Molecule Inhibitors to Disrupt Protein-protein Interactions of Heat Shock Protein 90 Chaperone Machinery. Seo YH. J Cancer Prev. 2015, 1, 5-11.

Nano-mechanical reinforcement in drug-resistant ovarian cancer cells. Seo YH, Jo YN, Oh YJ, Park S. Biol Pharm Bull. 2015, 3, 389-95.

Jeong CH, Park HB, Jang WJ, Jung SH, Seo YH. “Discovery of hybrid Hsp90 inhibitors and their anti-neoplastic effects against gefitinib-resistant non-small cell lung cancer (NSCLC)” Bioorg Med Chem Lett. 2014, 24, 224-7.

Lee T, Seo YH.” Targeting the hydrophobic region of Hsp90's ATP binding pocket with novel 1,3,5-triazines” Bioorg Med Chem Lett. 2013, 23. 6427-31

Seo, Young Ho “Discovery of Licochalcone A as a Natural Product Inhibitor of Hsp90 and Its Effect on Gefitinib Resistance in Non-Small Cell Lung Cancer (NSCLC)” Bull. Korean Chem. Soc. 2013. 34, 1917

Li Y, Karagöz GE, Seo Young Ho, Zhang T, Jiang Y, Yu Y, Duarte AM, Schwartz SJ, Boelens R, Carroll K, Rüdiger SG, Sun D “Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.” J Nutr Biochem. 2012, 23, 1617.

Truong, Thu H; Garcia, Francisco J; Seo, Young Ho; Carroll, Kate S. “ Isotope-Coded Chemical Reporter and Acid-Cleavable Affinity Reagents for Monitoring Protein Sulfenic Acids” Bioorganic & Medicinal Chemistry letters, 2011, 21, 5015.

Seo, Young Ho; Carroll, Kate S. “Quantification of Protein Sulfenic Acid Modification Using Isotope-Coded Dimedone and Iododimedone (ICDID)” Angewandte Chemie International Edition, (2011), 50, 6, 1342. Accepted as a Very Important Paper (VIP) and Highlighted in ScienceDaily, 2011, 1, 7. 

Seo, Young Ho; Carroll, Kate S. “Profiling Protein Thiol Oxidation in Tumor Cells Using Sulfenic Acid-specific Antibodies.” PNAS, 2009, 106, 16163. Highlighted in University Michigan News Service, 2009, 9, 7 and commercialized in US market.

Seo, Young Ho; Carroll, Kate S. “Facile Synthesis and Biological Evaluation of a Cell-Permeable Probe to Detect Redox-Regulated Proteins.” Bioorganic & Medicinal Chemistry letters, 2009, 19, 356. 

Reddie, Khalilah G.; Seo, Young Ho; Muse, Wilson B.; Leonard, Stephen E.; Carroll, Kate S. “A chemical approach for detecting sulfenic acid-modified proteins in living cells.” Mol. BioSyst., (2008), 4(6):521-31. Highlighted in Nature chemical biology, (2008), 4(5), 227 and Highlights in Chemical biology from across RSC Publishing, 2008, 3,14.

Kraus, George A.; Cui, Wenge; Seo, Young Ho “The reaction of aryl triflates and aryl pivalates with electrophiles - The triflate as a meta-directing group.” Tetrahedron Letters (2002), 43(39), 7077-7078.